Publications

Key Publications for Fludase for the treatment of Influenza

  • Marjuki  H. Mishin VP, Chesnokov AP, De La Cruz JA, Fry AM, Villanueva J, Gubareva LV
    An Investigational Antiviral Drug, DAS181, Effectively Inhibits Replication of Zoonotic Influenza
    A Virus Subtype H7N9 and Protects Mice From Lethality, J Infect Dis. 2014 Apr 1.
  • Moss RB, Hansen C, Sanders RL, Hawley S, Li T, Steigbigel RT, A Phase II Study of DAS181, a Novel Host Directed Antiviral for the Treatment of Influenza Infection, J Infect Dis. 2012 Dec 15;206(12):1844-51.doi10.1093/infdis/jis622. Epub 2012 Oct 8.
  • Moss RB, Dave RT, Steigbigel RT, Fang F, Targeting Pandemic Influenza:  a primer on Influenza Antivirals and Drug Resistance., J Antimicrob Chemother. 2010 Jun;65(6):186-93.doi: 101093/jac/dkq100. Epub 2010 Apr. 7. Review
  • Triana-Baltzer GB, Gubareva LV, Klimov Al, Wurtman DF, Moss RB, Hedlund M, Larson JL, Belswhe RB, Fang F.  Inhibition of Neuraminidase Inhibitor-Resistant Influenza Virus by DAS181, a Novel Sialidase Fusion Protein, PLoS One, 2009 Nov 6;4(11):e7838.doi: 10.1371/journal.pone.0007838.
  • Triana-Baltzer GB, Gubareva LV, Nicholls JM, pearce MB, Mishin VP, Belser JA, Chen LM, Chan RW,  Chan MC, Hedlune M, Larson JL, Moss RB, Katz JM, Tumpey TM, Fang F., Novel Pandemic Influenza A(H1N1) Viruses are Potently Inhibited by DAS181, a Sialidase Fusion Protein, PLoS One.  2009 Nov 6;4(11):e7788. Doi:  10.1371/journal.pone.0007788

Key publications for Paradase for the treatment of  Parainfluenza Virus  in Immunocompromised Patients

  • Guzmán-Suarez, BB, Buckley, MM, Gilmore, ET, Vocca, E, Moss, R, Marty, FM,  Baden, LR,  Issa, NC, Koo S. Clinical Potential of DAS181 for Treatment of Parainfluenza-3 Infections in Transplant Recipients, Transplant Infectious Disease, 2012
  • Chen, YB, Driscoll, J, McAfee, SL, Spitzer, TR, Rosenberg, E, Sanders, R, Moss R, Fang, F, Marty, F, Treatment of Parainfluenza 3 Infection with DAS181 in a Patient After Allogeneic Stem Cell Transplantation, Journal of Clinical Infectious Disease, 2011
  • D.R. Drozd, A.P. Limaye, R.B. Moss, et. al.,DAS181 Treatment of Severe Parainfluenza Type 3 Pneumonia in a Lung Transplant Recipient, Transplant Infectious Disease, ISSN 1398-2273, 2012
  • S. Chalkias, M.R. Mackenzie, C. Gay, C. Dooley, F.M. Marty, R.B.Moss, T. Li, R.L. Routh, S.R. Walsh, C.S. Tan. DAS18 1 Treatment of Hematopoietic Stem Cell Transplant Patients with Parainfluenza Virus Lung Disease Requiring Mechanical Ventilation, Transpl Infect Dis 2013
  • Wagmire, A, Wagnor, T., Andrews, R., Smith, S, Kupyers, J., Boeckh, M, Moss, R., Englund, J, Successful Treatment of Parainfluenza Virus Respiratory Tract Infection With DAS181in 4 Immunocompromised Children, J Ped Inf Disease, pp. 1–5, 2014. DOI:10.1093/jpids/piu039